 
1)
2)
1) In the cerebral cortex of the brain there
are soap bubble cysts full of organism,
Cryptococcus Neoformans.
Only the centre of the organism is visible, the thick gelatinous capsule
remaining unstained.
2) This shows another cyst
in the superficial cortex of the brain which contains large numbers of the
organism.
There is relatively less microglial reaction in the underlying cortex
(left) but in the subarachnoid space (right) there is fibroplasia and giant cell
reaction.
Characteristic
microscopic "soap-bubble"
appearance of
Cryptococcus Neoformans.
(Visit:
Pathology of Cryptococcosis
)
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