adenocarcinoma consists of predominantly fibrovascular
stalks lined by malignant epithelial cells, and it often produces
mucin in the gallbladder.
papillary adenocarcinoma consists of branching fibrovascular
stalks lined by atypical cuboidal or columnar cells.
Papillary carcinomas tend to fill the lumen of the gallbladder
before invading the gallbladder wall.
invading portion of the tumour forms tubular structures
rather than papillae. Both patterns may be seen in metastatic
Metastatic lesions in the liver and regional lymph nodes
are rarely noted with this tumour.
adenocarcinoma has a better prognosis than other variants.