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Gallbladder Pathology Online

Pathology of Gallbladder Infections

Dr Sampurna Roy  MD


Specific Gallbladder Infections:

Visit: Infectious Disease Online

Salmonella typhi, Campylobacter jejuni, Escherichia coli Infection , Brucellosis and Tuberculosis have all been found in the gallbladder.

Visit: Campylobacter Infection

Fungi have been found in up to 10% of cholecystectomy specimens but in our experience this really not at all common.

Fungi would be expected more commonly in debilitated or immunosuppressed patients and the fungi in question would be Candida.   

Visit: Candidosis (Candidiasis)

These may give rise to granulomatous cholecystitis so it is usually worth checking for fungi and acid and alcohol fast bacilli in any granulomatous cholecystitis.

Cytomegalovirus infection may cause obstruction of the cystic duct by enlargement of mucosal lining cells.

This is seen mainly following orthotopic liver transplantation.

Protozoal infections are unusual. They include Giardia lamblia and cryptosporidium usually in immune deficient patients.

Visit: Giardiasis ; Cryptosporidium

Typhoid gallbladder:  Typhoid carriers ‘harbor’ living Salmonella typhi in their gallbladder and their gallstones The organisms are discharged into the alimentary tract from time to time, and are present in the feces.   These cases are potential danger to the community.

 Visit: Typhoid fever ; Salmonellosis (Gastroenteritis and Septicemia)

Worms detected in the gallbladder:

Platyhelminths - Fasciola hepatica , Paragominus westermani and ascaris lumbricoides, along with Chlonorchis sinensis have been identified but are rare.  

Visit: Fascioliasis and Fasciolopsiasis  ; Ascariasis  ; Paragonimiasis Clonorchiasis ; Echinococcosis (Hydatid Disease).

Hydatid disease is usually seen in the common bile duct as a result of rupture of a hydatid cyst within the liver.

More worms are encountered within the biliary system than are seen in the gall bladder itself.


 Further reading:

Gallbladder ascariasis.

Successful elimination of Ascaris lumbricoides from the gall bladder

Ascariasis of gall bladder associated with xantho granulomatous inflammation  

Biliary Ascariasis in the Indian Subcontinent

Infection as a risk factor for gallbladder cancer

Chronic and acute infection of the gall bladder

Role of bile bacteria in gallbladder carcinoma.

Acute acalculous cholecystitis: A rare presentation of  typhoid fever in adults. 

Enterocytozoon bieneusi infection in acquired immunodeficiency syndrome - related sclerosing cholangitis  

Biliary fascioliasis: sonographic appearance patterns.

Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis




Dr  Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)











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