blog counter

 

      

 

 

 

 

                                                                  

                                    

                              

Gallbladder Pathology Online

Pathology of Squamous and Adenosquamous Cell Carcinoma of the Gallbladder

Dr Sampurna Roy MD

 

Squamous and adenosquamous cell carcinomas of the gallbladder are rare.

 

Microscopic image of adenosquamous carcinoma

The adenosquamous carcinoma contains a mixture of malignant glandular and squamous components.

The pure squamous cell carcinoma constitutes only 1% of all malignant gallbladder tumors and consists of cords, islands, or sheets of malignant squamous cells separated by dense fibrous stroma.

These tumours most likely arise in areas of previous squamous metaplasia, and their histologic features may vary from anaplastic to well-differentiated, keratinizing squamous cell carcinoma.

Their clinical behavior and clinicopathologic characteristics are very different from those of adenocarcinoma.

The tumours characteristically tend to arise from the gallbladder fossa and present rapid and invasive growth, which results in direct invasion into the liver and adjacent organs.

In contrast to their aggressive tendency and advanced stage, they usually do not present lymph node metastasis or peritoneal seeding.

Liver metastases are more frequently seen, however, than with the adenocarcinoma.

 

Further reading:

Adenosquamous and squamous carcinoma of the gallbladder

Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible.

Adenosquamous carcinoma of the gallbladder with spindle cell features. A light microscopic and immunocytochemical study of the case.

Stromal osteoclast-like giant cells in an adenosquamous carcinoma of the gallbladder

Adenosquamous/squamous cell carcinoma of the gallbladder

Adenosquamous carcinoma of the gallbladder.

Adenosquamous carcinoma of the gall-bladder with gastric foveolar-type epithelium

Hepatopancreatoduodenectomy for squamous and adenoaquamous carcinoma of the gallbladder.

Adenosquamous carcinoma of the gallbladder: a clinicopathological, immunohistochemical and flow-cytometric study of twenty cases.

Albores-Saavedra J, Henson DE, Sobin LH. WHO histological typing of tumors of the gallbladder and extrahepatic bile ducts Berlin, Germany: Springer-Verlag, 1991.

 

 

 

 

 

 

 

          

 

 

 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Infectious Disease Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Gallbladder Pathology Online

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright 2017  pathology-india.com