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Gallbladder Pathology Online

Pathology of Mucinous Adenocarcinoma of the Gallbladder

Dr Sampurna Roy  MD 


Mucinous adenocarcinoma is a type of mucin-producing carcinoma and consists of a massive mucous pool within  the neoplastic tissues.

These tumours consist of more than 50%  extracellular mucin.

There are two histologic variants:


Microscopic images of mucinous adenocarcinoma of the gallbladder

a) Contains large pools of extracellular mucin with small clusters of malignant epithelial cells and 

b) those characterized by mucin-filled glands with cystic dilatation.

Foci of both variants may be found admixed with conventional, well-differentiated adenocarcinoma.

The tumour has a poor prognosis because of its tendency toward invasive growth.


Further reading:

Preoperative visualization of mucin-producing gallbladder carcinoma by using peroral transcatheter cholecystoscopy technique (with video).

Biphasic large cell neuroendocrine carcinoma--pure mucinous carcinoma of the gallbladder (MANEC): a unique combination.

[A case in which a mucin-producing papillary adenocarcinoma of the gallbladder was resected].

Mucin-producing carcinoma of the gallbladder: evaluation by magnetic resonance cholangiopancreatography in three cases.

Mucin-producing carcinoma of the gallbladder associated with primary sclerosing cholangitis and ulcerative colitis.

Mucin-producing gallbladder adenocarcinoma with focal small cell and large cell neuroendocrine differentiation associated with pancreaticobiliary maljunction.

Imaging findings in mucin-producing carcinoma of the gallbladder.

Mucin-producing carcinoma of the cystic duct that caused obstructive jaundice.

Mucin-producing carcinoma of the gallbladder: imaging demonstration in four cases.

[Mucin producing gallbladder cancer].

Albores-Saavedra J, Henson DE, Sobin LH. WHO histological typing of tumors of the gallbladder and extrahepatic bile ducts Berlin, Germany: Springer-Verlag, 1991.

Mucinous carcinomas of the gallbladder: clinicopathologic analysis of 15 cases identified in 606 carcinomas.  

Case of mucinous adenocarcinoma with porcelain gallbladder



Dr  Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)









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