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Dermatopathology Quiz Case 177

                    Dr Sampurna Roy  MD

November 2014 - Friday

82 year old lady with rapidly growing multiple reddish brown nodules on the left lower limb.

CD19, CD20 and CD79a positive. Bcl-2 protein is strongly expressed.  CD3, CD5, CD23 and cyclin D-1 are negative.


  Image 1  Cellular infiltrate involving the entire dermis. A bottom heavy infiltrate is seen.
 Image 2  There is a grenz zone between epidermis and the infiltrate.
 Image 3  Diffuse infiltrate of large cells with nuclei twice the size of the lymphocyte.
 Image 4 The neoplastic cellular infiltrate has a mixed population of centroblasts, immunoblasts and a few large cleaved centrocyte-like cells.
 Image 5 A - High power view: 5 sections of the neoplastic lesion from different  areas demonstrating the polymorphous infiltrate in the dermis.
 Image 5 B  
  Image 5 C 
 Image 5 D   
  Image 5 E   



                   List of all previous dermatopathology cases


Dr  Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


  Ref:  Dermpath-India  ;  Surgical ; ; Pancreatic Pathology Online Gallbladder Pathology Online ; Dermpath-India ; Infectious Disease Online-IndiaPathology Quiz Online  ; Paraganglioma-Online ; Endocrine Pathology Online  ; Paediatric Pathology Online ; Eye Pathology Online Ear Pathology Online ; Cardiac Path Online ; Pulmonary Pathology Online Lung Tumour-Online ; Nutritional Pathology Online ; Environmental Pathology Online  ;  Soft tissue Tumour Online-India  ; GI Path Online-India ; Case Index ; Mesothelioma-Online ; E-book - History of Medicine with special reference to India.



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