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Dermatopathology Quiz Case 160

 Dr Sampurna Roy  MD

August 2014 - Friday

Case history

A 30 year old female with a history of recurrent self healing crusted papules on the legs and face for 1 year. The papules completely disappeared for several weeks and again reappeared. These are histopathology sections of the papules.

Immunohistochemistry showed that the cells are CD30 positive. CD3, CD4 and CD8 are negative.


    There are atypical lymphoid cells extending throughout the dermis The lymphocytes have large pleomorphic nuclei. Some binucleate lymphocytes resemble Reed-Sternberg's cells and multinucleate abnormal lymphocytes are also present.
  High power view showing a heavy mixed infiltrate. The large dark cells with hyperchromatic nuclei are clearly visible in the dermis. These cells are described as "chunks of coal".
  Further section of the papule showing more atypical lymphoid cells similar to "chunks of coal"
   The cells are CD30 positive.


                     List of all previous dermatopathology cases


Ref: Dermatopathology website:

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