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Dermatopathology Quiz Case 151

 Dr Sampurna Roy  MD

 June 2014 - Friday


Case history

A 75 year old woman with a macerated, oozing lesion of the vulva. CK7 and EMA positive. S100 protein negative.

 Image 1 - Low power view of the lesion located in the epidermis.
  Image 2- There are single and small clusters of atypical cells in the epidermis. The tumour cells are located mainly at the base of the epidermis. Some cells have infiltrated into the upper portion of epidermis.
   Image 3 - High power view showing nests of atypical tumour cells and prominent intracytoplasmic vacuoles.
Image 4- The intraepidermal tumour cells are large with amphophilic, granular cytoplasm and prominent atypical nucleus.
Image 5- Further high power view of the same intraepidermal tumour.


Dr  Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


                     List of all previous dermatopathology cases

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