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Gallbladder Pathology Online

Pathology of Acalculous Cholecystitis

Dr Sampurna Roy  MD    


Acalculous cholecystitis accounts for 10% of cases of all cases of acute cholecystitis.

In comparison to ordinary acute cholecystitis, acalculous cholecystitis has a higher likelihood of gangrene and perforation and as well as significantly higher morbidity and mortality rate.

It is more common in the elderly and in male patients.

Patients are usually severely debilitated, due to severe trauma, sepsis, shock, burns or other disease conditions.

Acalculous cholecystitis may complicate hypotension in trauma, surgery, child birth, burns, septicemia or hyperalimentation and in AIDS or bone marrow transplantation or in association with diabetes mellitus. 

The trauma, burns or surgery usually precede the on-set of cholecystitis by two weeks. 

The histology is like that of acute cholecystitis.

Visit: Acute cholecystitis ; Emphysematous cholecystitis.


Further reading:

The increasing prevalence of acalculous cholecystitis in outpatients. Results of a 7-year study.

Acute acalculous cholecystitis as the initial presentation of primary Epstein Barr virus infection 

Acute acalculous cholecystitis as the initial presentation of Primary Epstein Barr virus infection

Cellular turnover and expression of hypoxic-inducible factor in acute acalculous and calculous cholecystitis

Tight junction proteins in gallbladder epithelium: different expression in acute acalculous and calculous cholecystitis 

Acute acalculous cholecystitis in a child returning from the Ivory Coast

Acute acalculous cholecystitis: pathophysiology and treatment

Acute acalculous cholecystitis in a child with systemic lupus erythematosus

Acute acalculous cholecystitis following open heart surgery

Familial acalculous gallbladder disease.

Acalculous cholecystitis in bone marrow transplant patient

A case of acute hemorrhagic gangrenous acalculous  cholecystitis with bile peritonitis during anti-coagulant therapy after coronary artery bypass grafting

Hepatobiliary manifestations in AIDS in adults.Place of Cholecystectomy 

Diagnosis of gallbladder perforation in acute acalculous cholecystitis in critically ill patients

Acalculous cholecystitis due to Salmonella enteritidis

Acalculous acute cholecystitis due to Salmonella typhi

Acute acalculous cholecystitis caused by Salmonella typhi in a 6 year old child.





Dr  Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)










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