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Schwannoma with neuroblastoma-like
rosettes: an unusual morphologic variant.Am
J Dermatopathol. 2005 Jun;27(3):243-6.
In the past ten years,
seven cases of schwannomas with giant fibrillar rosettes or perivascular
rosettes have been reported. As these unusual variants of schwannomas had
areas with hyperchromatic, small round cells recapitulating the appearance
of a neuroblastoma, they received the descriptive name of neuroblastoma-like
schwannomas. We herein report two additional cases of this unique variant of
schwannoma and provide differential diagnostic considerations.
Neuroblastoma-like schwannoma:
a case report and review of the literature.Am
J Dermatopathol. 2003 Feb;25(1):32-4.
We report a case of
schwannoma (neurilemmoma) predominantly composed of small cells arranged in
rosettes around central collagenous cores and discuss the differential
diagnosis of this unusual variant. Schwannoma with giant rosettes,
previously designated as neuroblastoma-like schwannoma by Goldblum et al.,
must be differentiated from neuroblastoma, peripheral neuroectodermal
tumors, and malignant change in a schwannoma.
Rosetoid schwannoma (neuroblastoma-like)
in association with an anetoderma.J
Cutan Pathol. 2006 Aug;33(8):573-6.
BACKGROUND: We report
an additional case of an extremely uncommon but distinctive histological
variant of benign schwannoma, which was previously designated as
neuroblastoma-like schwannoma by Goldblum et al. METHODS: A 29-year-old
woman referred to a 6-year-history of an atrofic macule. Its clinical
appearance was similar to that of an anetoderma. RESULTS: A cutaneous biopsy
showed findings consistent with a neuroblastoma-like schwannoma with the
following peculiar features: (i) Being fully composed of rosette-like
structures. (ii) Association to an anetoderma. CONCLUSIONS: Because neither
the histological pattern nor the type of tumor allows a differential
diagnosis with neuroblastoma, we propose the descriptive term of rosetoid
schwannoma. And to our knowledge, this will be the first case reported of
rosetoid schwannoma associated to anetoderma. |
