|Syn: Ectopic and
Metaplastic Tissue of the Gallbladder:
Heterotopic tissue commonly
present in the gallbladder include liver, pancreas, gastric and
In rare cases thyroid
follicle and adrenal tissue may be found in the wall of the
Pancreatic tissue may
include islets of Langerhans, together with exocrine pancreas.
Heterotopic island of
gastric mucosa together with chief and parietal cells are commonly
present at the neck and fundus of the gallbladder. Macroscopically the
gastric mucosa may be polypoid or plaque-like. The gastric mucosa may
replace the normal mucosa or may form intramural nodule.
foci of gastric mucosa should be distinguished from antral or gastric
surface epithelium which is a metaplastic process. Metaplastic gastric
mucosa is usually found in elderly patient. Enterochromaffin cells,
goblet cells and paneth cells may be found in association with
metaplastic antral or gastric mucosa.
may be present in papilloma of gallbladder. Goblet cell metaplasia and
prominent hyperplasia of mucous glands are seen near carcinomas of
Squamous metaplasia is
seen near squamous cell carcinoma, specially in Porcelain gallbladder.
should be anatomically separate from the the main organ.