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 Metastatic Tumours of Gall Bladder

 

 

                

Secondary malignancy is found in the gall bladder in 0.025% of all autopsies and 5% of patients dying of carcinoma.

The common tumours to metastasize to the gall bladder are from the stomach, pancreas, breast, colon, kidney and lung and  malignant melanoma.

 Ultrasound patterns of metastatic tumors in the gall bladdder.Journal of Clinical Ultrasound.Volume 10, Issue 8 , Pages 379 - 383

Eleven cases of sonographically detected metastatic disease to the gallbladder are reported. This paper represents the first comprehensive review of the ultrasonographic findings in this not infrequently encountered disease process. Four distinctive sonographic diagnostic patterns have evolved and are described. The suspicion of metastatic tumors in the gallbladder should be raised, particularly in the presence of focal gallbladder wall thickening in association with nonshadowing intraluminal soft tissue masses. In contrast to primary carcinomas of the gallbladder, cholelithiasis usually is absent. The differential diagnosis, which includes various benign conditions of the gallbladder, is discussed.

Renal cell carcinoma metastatic to gallbladder: a survival advantage to simultaneous nephrectomy and cholecystectomy.Int Urol Nephrol. 2007;39(2):377-9. Epub 2007 Feb 17.

Renal cell carcinoma is a relatively uncommon cancer. Patients presenting with a renal adenocarcinoma are often found to have evidence of metastatic disease at the time of diagnosis. Herein, we describe the case of a 39-year-old male with renal cell carcinoma and a synchronous metastatic focus to the gallbladder. The patient underwent a successful simultaneous nephrectomy and cholecystectomy and is doing well 30 months after surgery without evidence of disease recurrence. A thorough metastatic work-up along with aggressive surgical intervention in patients with renal cell carcinoma and unusual metastatic foci can provide a long-term favorable outcome.

                     

Isolated gall bladder metastasis from renal cell carcinoma.Indian J Gastroenterol. 2006 May-Jun;25(3):161-2.

Gall bladder metastasis from renal cell carcinoma is rare. We report a 46-year-old man with isolated gall bladder metastasis from renal cell carcinoma 11 months after radical nephrectomy. He underwent cholecystectomy and frozen section revealed the metastatic tumor. Sixteen months later, the patient is free of disease.

Gallbladder metastasis of Non Small Cell Lung Cancer.Onkologie 2004;27:398-400

Background: Although non-small cell lung cancer is known for its potency to spread to almost any organ of the body, metastasis to the gallbladder with significant clinical manifestation is rarely reported in the literature. Case report: We report the case of a 45-year-old man with non-small cell lung cancer (NSCLC), who developed symptoms of acute cholecystitis caused by a metastasis of the gallbladder wall. Histological examination showed tumor cell invasion in regional gallbladder lymph nodes. A second primary tumor of the gallbladder was excluded by immunohistochemical methods. Conclusion: Our experience showed that acute cholecystitis can occur in association with metastases of lung cancer to the gallbladder.

 

January 2008
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Anatomy of Gall Bladder

Arterial and Lymphatic Supply of Gall Bladder

Physiology of Gall Bladder

Macroscopic examination and dissection of Gall Bladder