| Desmoplastic
fibroblastoma: a case presenting as a protruding nodule in the dermis.J
Cutan Pathol. 2008 Jun 9.
Desmoplastic
fibroblastoma is a rare, benign, soft tissue tumor. We describe a case of
superficial desmoplastic fibroblastoma presenting as a protruding nodule. A
41-year-old woman presented with a painless, firm, elevated nodule with
ulceration on her left thigh. Histological examination from total excision
showed a well-circumscribed tumor in the dermis, which comprised of spindle,
oval and stellate cells arranged in a haphazard fashion, accompanied by
abundant collagenous stroma and inconspicuous vasculature.
Immunohistochemically, the tumor cells were positive for vimentin, and
focally positive for alpha-smooth muscle actin and muscle-specific actin,
but negative for CD34, S-100 protein, desmin and beta-catenin. We diagnosed
this case as desmoplastic fibroblastoma arising in the dermis and
superficial subcutaneous tissue.
Desmoplastic fibroblastoma
of the foot.Rev
Chir Orthop Reparatrice Appar Mot. 2008 Apr;94(2):188-92. Epub 2008
Feb 20.
Desmoplastic
fibroblastoma is a benign, rare, slow-growing soft tissue tumor which is
found in a wide anatomic distribution, predominantly in adult males. The
characteristic gross aspect is that of a typical cartilage-like tumor which
histologically presents regular fibroblastic proliferation, often in a
stellar shape within a dense collagen or myxo-collagen stroma. We report a
new case observed in the foot and study the anatomic and clinical aspects of
this rare entity.
Collagenous fibroma (desmoplastic
fibroblastoma): a new case originating in the palate.
Dentomaxillofac Radiol. 2005 Mar;34(2):117-9.
A 49-year-old woman
presented with a painless slowly growing but huge polypoid palatal mass. On
magnetic resonance imaging (MRI), areas of low signal intensity were
consistent with a fibrous tumour. T(1) and T(2) weighted MRI after Gd-DTPA
administration highlighted a well-circumscribed, purely soft tissue process.
Histological analysis of the operative specimen detected collagenous fibroma
(desmoplastic fibroblastoma). The patient remains disease-free 4 years after
excision. |
