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Sonographic findings of dermato fibrosarcoma protuberans with
pathologic correlation.J
Ultrasound Med. 2008 Feb;27(2):269-74.
OBJECTIVE: The
purpose of this series was to describe the sonographic features of
dermato fibrosarcoma protuberans (DP) and correlate them with the
pathologic findings of this condition. METHODS: The echogenicity and
marginal contour of DP in 4 patients were observed on sonography, and
these features were then correlated with the cellular components and
histologic grading of pathologic specimens. Additionally, color
Doppler sonography was conducted to evaluate the distribution of blood
flow signals in the tumors. RESULTS: All lesions were located in the
subcutaneous fat layer, abutted against the skin, and had a wide base.
Two of the cases of DP observed on the sonograms were hypoechoic, and
2 had mixed echogenicity; however, the mixed echogenic tumors were
primarily echoic. The margin was focally lobulated but well defined in
the hypoechoic tumors; however, the margin appeared as an irregular
pseudopodialike protrusion in the mixed echogenic tumors. Color
Doppler sonography showed 2 different blood flow patterns: 1 in which
profuse blood flowed through the entire tumor and 1 in which only a
small amount of blood flowed through the peripheral portions of the
tumor. The 2 blood flow patterns were observed in 1 of each type of
tumor. Pathologically, samples corresponding to hypoechoic DP were
composed primarily of tumor cells, and samples corresponding to mixed
echogenic DP were composed of tumor cells and fibrous tissues.
CONCLUSIONS: If a sonogram reveals an oval mass in the subcutaneous
tissue that is abutting against the skin and has a focal lobulated
margin with hypoechogenicity or an irregular margin with mixed
echogenicity, a diagnosis of DP should be considered.
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Dermatofibrosarcoma Protuberans
Visit:
Dermpath-India
| Dermatofibrosarcoma
protuberans, magnetic resonance imaging and pathological
correlation.
Australas
Radiol.
2007 Oct; 51 Spec No.:B64-6.
Dermatofibrosarcoma protuberans (DFSP) is a rare slow-growing soft
tissue tumour which characteristically occurs on the chest, head and
neck regions. Typical histologic features include monomorphous
spindle-shaped cells arranged in a storiform pattern on a background
of fibrous stroma. The tumour has a propensity for local invasion
and high recurrence rate. While the imaging features are not
pathognomonic of the tumour, the characteristic location and shape
should prompt inclusion in the differential diagnostic list. |
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March 2008
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