Lipomas are common neoplasms of fat in the oral cavity. However, the diagnosis may be difficult for lesions exhibiting unusual histological features. This paper documents the first intraoral report of a chondroid lipoma. The differential diagnosis is discussed. It is important for practicing oral pathologists to recognize rare variants to ensure accurate diagnosis and appropriate treatment for the patient.

Chondroid lipoma of the trunk: MRI appearance and pathologic correlation.Skeletal Radiol. 2004 Nov;33(11):666-9. Epub 2004 May 5.

Chondroid lipoma is a rare tumour of adipose tissue, bearing a strikingly close pathologic resemblance to myxoid liposarcoma and extraskeletal myxoid chondrosarcoma. Unlike these malignant tumours, chondroid lipoma has a non-aggressive behaviour and does not require radical treatment. Although repeatedly reported in the proximal extremities and limb girdles, this rare entity may less frequently be observed in the trunk. We describe the imaging findings of a chondroid lipoma in the trunk and provide a discussion on the radiologic-pathologic correlation and differential diagnosis.