blog counter
 

 

                                      HISTOPATHOLOGY INDIA.COM

                  Histopathology Image of

                Atypical Fibroxanthoma 3

                            

Custom Search

Nodular fasciitis

Proliferative fasciitis

Proliferative myositis

Ischaemic fasciitis

Elastofibroma

Fibrous Hamartoma of Infancy

Infantile Myofibromatosis

Juvenile hyaline fibromatosis

Inclusion  Body Fibromatosis

Calcifying aponeurotic fibroma

Fibromatosis colli

Fibroma of tendon sheath

Desmoplastic fibroblastoma  

 Storiform Collagenoma  

 Giant Cell Collagenoma

FUNCTIONAL ANATOMY OF THE HEART

ANATOMY OF THE ATRIUM

ANATOMY OF THE VENTRICLE

ANATOMY OF THE CORONARY ARTERIES

AUTOPSY EXAM. OF CORONARY ARTERIES

EXAMINATION  OF CARDIAC  VALVES

CARDIAC  VALVE  DISEASE

MITRAL  VALVE LESIONS

PULMONARY VALVE DISEASE

TRICUSPID VALVE DISEASE

CARDIOMYOPATHY

CONGESTIVE HEART FAILURE

congenital heart disease

Ischemic heart disease

Angina pectoris

Myocardial infarction       
 
hypertensive heart disease
 
RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
 
PATHOLOGY OF ASCHOFF BODIES OR NODULES
 
myocardiTIS
 
GIANT CELL MYOCARDITIS
 
pericardial disease  

INFECTIVE ENDOCARDITIS

CARDIAC HEMOCHROMATOSIS

CARDIAC AMYLOIDOSIS

HISTOPATHOLOGY REPORTING OF PERICARDIAL SPECIMEN

HEART TRANSPLANTS - PATHOLOGICAL EXAMINATION

ENDOMYOCARDIAL BIOPSY-(ALLOGRAFT REJECTION):

ISHLT SYSTEM FOR GRADING REJECTION

POST-OPERATIVE CARDIAC PATHOLOGY

Atypical Fibroxanthoma

Visit:  Soft Tissue Pathology

Your Ad Here
CD99 immuno-reactivity in atypical fibroxanthoma and pleomorphic malignant fibrous histiocytoma: a useful diagnostic marker.J Cutan Pathol. 2006 Sep;33 Suppl 2:24-8.

Atypical fibroxanthoma (AFX), a benign lesion, and pleomorphic malignant fibrous histiocytoma (MFH) are thought to represent points along the same neoplastic spectrum but with different prognoses and treatments. Diagnosis based on histology and clinical parameters alone is sometimes difficult, and a reliable cost-effective immunohistochemical marker to help distinguish these lesions would be beneficial. The diagnosis of AFX or MFH was based upon published clinical and microscopic criteria. Formalin-fixed, paraffin-embedded tissues of 17 cases of AFX and 26 cases of MFH were immunostained with monoclonal antibody to CD99. For all cases, CD99 expression was scored on a four-tiered scale: negative, weak (1+), moderate (2+), or strong (3+). Two pathologists blinded to tumor diagnoses and type of immunostain evaluated each case independently. The interobserver correlation coefficient was calculated. Seventeen patients with AFX (16 males and one female; mean age = 79) and 26 patients with MFH (16 males and 10 females; mean age = 60) were included. AFX lesions were from the head and the face, mean size = 1.5 cm, and MFH lesions were from the head, the neck, the trunk, and the upper/lower extremities, mean size = 5.2 cm. The 17 cases of AFX demonstrated moderate or strong (2 to 3+) immunoreactivity with CD99, compared to nine of 26 (35%) MFH cases (chi-square = 18.38; p < 0.001; interobserver correlation coefficient = 0.83). Of these, 16 of 17 (94%) AFX cases stained diffusely with CD99, while only four of 26 (15%) MFH cases stained diffusely. Control slides were adequate. Our study demonstrated that CD99 can help distinguish AFX from MFH, in addition to other immuno- histochemistry as well as clinical and histologic criteria.

Granular cell atypical fibroxanthoma: report of two cases.Am J Dermatopathol. 2007 Feb;29(1): 84-7.

Two cases of an uncommon histopathological variant of atypical fibroxanthoma (AFX) are described. Even though both lesions presented as clinically conventional atypical fibroxanthoma, histopathology disclosed a neoplasm composed of cells with granular change that was negative for S100 staining, and showed prominent pleomorphism, severe nuclear atypia, and a high mitotic index. Degenerative change may explain the granular phenotype in these two cases of AFX. The differential diagnosis with primitive nonneural granular cell tumor is discussed.

Custom Search
June 2009

Histopathology-India.net

diagnostichistopathology. blogspot.com

Pathopedia-India.com

Surgical-Pathology.com

Pathology-India.com

Pancreatic Pathology Online

Gall Bladder Pathology Online

Paediatric Pathology Online

Paraganglioma-Online

Endocrine Pathology Online

Eye Pathology Online

Ear Pathology Online

Cardiac Path Online

Lung Tumour-Online

Mesothelioma-Online

Pulmonary Pathology Online

Nutritional Pathology Online

Environmental Pathology Online

Pathology Quiz Online

Dermpath-India

GI Path Online

Soft Tissue Pathology

Case Index

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

E-book - History of  Medicine with special reference to India

Basic Pathology Blog


                                                Disclaimer  ;  Privacy Policy  ; Advertising Policy  ;  E-mail 

                                                                        Copyright © 2009 pathology-india.com
                                                                                      All rights reserved