Angiolymphoid hyperplasia with eosinophilia is a rare condition that demonstrates dermal or subcutaneous proliferation of endothelial cells associated with an inflammatory cell infiltrate. A case is reported, with emphasis on the histopathological features on repeated biopsies. The report serves to stress the importance of considering this condition in the differential diagnosis of lesions in and around the ear.

Protruding tumorous angiolymphoid hyperplasia with eosinophilia (ALHE) of the scalp accompanied by arterial occlusion.J Dermatol. 2002 Jan;29(1):38-42.

We report a case of an extraordinarily large tumorous form of ALHE developing on the occiput of a 57-year-old Japanese male. Histologically, it was characterized by increased numbers of small blood vessels, fibrosis, and lymph follicle formations with massive eosinopilia in the dermis in addition to an occluded artery in the deep dermis.

Angiolymphoid hyperplasia of the head and neck.J Laryngol Otol. 1988 Jan;102(1):100-1.

Angiolymphoid hyperplasia is a rare benign condition affecting the skin and subcutaneous tissue of the head and neck. Superficial (intradermal) lesions frequently affect the external ear and such a case presenting to an otolaryngologist is described. Clinically the disease is characterized by single or multiple plum-coloured nodules or plaques which are often itchy and may bleed with mild trauma. Histologically the lesions are composed of proliferating capillary vessels associated with a heavy inflammatory infiltrate including eosinophils and mast cells. The cause remains obscure. The lesions often persist for many years and may regress spontaneously. Several forms of treatment have been used, including cryosurgery, curettage and diathermy, radiotherapy and intralesional steroid injections. In this case the Argon laser was employed.