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Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia)
of the orbit: a case report.J
Med Case Reports. 2007 Jun 25;1:30.
ABSTRACT:
BACKGROUND: Angiolymphoid hyperplasia with eosinophilia (ALHE) and
Kimura's Disease (KD) share many clinical and histopathological
features. Although they were once considered different stages of the
same disease, they are now known to represent separate entities.
Recently, ALHE is being called epithelioid hemangioma (EH), a term
that better describes the possible neoplastic nature of the entity.
CASE PRESENTATION: An eighteen year-old Asian female presented with
a three-month history of fluctuating swelling and ptosis of the left
upper eyelid. Computed tomography disclosed a distinct homogeneous
lesion in the left superior orbit, molding to the globe and other
orbital structures. At histopathological evaluation the lesion was
composed of numerous blood vessels lined by plump endothelial cells
with oval nuclei protruding into the lumen. Surrounding the vessels,
there was a chronic inflammatory infiltrate with a large proportion
of eosinophils. Based on clinical and histopathological findings,
the diagnosis of EH was made. CONCLUSION: Although exams like blood
count, urinalysis and whole body scans can assist in the
differential diagnosis, EH can be diagnosed and differentiated from
KD on histopathological grounds. The presence of vascular
hyperplasia with plump endothelial cells protruding into the lumen
is the most important discriminator in establishing the diagnosis of
EH. Such distinction is crucial for the patient because EH is not
associated with any of the systemic manifestations present in KD.
Angiolymphoid
hyperplasia with eosinophilia of the parapharyngeal space.J
Laryngol Otol. 1998 Aug;112(8):802-4.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon
benign condition characterized by cutaneous nodules with a
predeliction for the head and neck region. Extracutaneous
involvement is rare. We report a 44-year-old woman who had a large
submucosal ALHE tumour in the parapharyngeal space. Our patient is
of interest because of the unusual, and as far as we are aware from
the literature, unique site and presentation of her lesion. |
